Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Viral Infection: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Associated Genes | CYTOKINES, ALZHEIMER, INFLAMMATION, CANCER, ALZHEIMER'S DISEASE, VIRAL INFECTIONS, AUTOPHAGY, AGING |
| Therapeutic Agents | ISR Potentiators, Isr Potentiators |
| KG Connections | 342 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
Knowledge base pages for this entity
graph TD
Viral_Infection["<b>Viral Infection</b>"]
Inflammation{"Inflammation"}
Viral_Infection -->|"activates"| Inflammation
Apoptosis["Apoptosis"]
Viral_Infection -->|"activates"| Apoptosis
Immune_Response["Immune Response"]
Viral_Infection -->|"associated_with"| Immune_Response
Innate_Immunity["Innate Immunity"]
Viral_Infection -->|"causes"| Innate_Immunity
Infection{"Infection"}
Infection -->|"activates"| Viral_Infection
VIRAL_INFECTIONS(["VIRAL INFECTIONS"])
VIRAL_INFECTIONS -->|"associated_with"| Viral_Infection
style Viral_Infection fill:#1a3a4a,stroke:#ef5350,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Endoplasmic Reticulum | associated_with | organelle | 0.95 |
| Inflammation | activates | disease | 0.85 |
| Reticulophagy | modulates | process | 0.85 |
| HMGB1 | upregulates | protein | 0.80 |
| Inflammation | causes | disease | 0.75 |
| Apoptosis | activates | pathway | 0.70 |
| Immune Response | associated_with | pathway | 0.70 |
| Immune Response | activates | pathway | 0.70 |
| Innate Immunity | causes | pathway | 0.70 |
| Immune Response | causes | pathway | 0.70 |
| Autoimmune | activates | disease | 0.65 |
| Alzheimer | associated_with | disease | 0.65 |
| Inflammation | treats | disease | 0.65 |
| Alzheimer | activates | disease | 0.65 |
| Neurodegeneration | associated_with | disease | 0.65 |
| Inflammation | interacts_with | disease | 0.65 |
| Drug Resistance | activates | pathway | 0.60 |
| Cell Division | therapeutic_target | pathway | 0.60 |
| Autophagy | associated_with | pathway | 0.60 |
| Senescence | associated_with | pathway | 0.60 |
| Inflammasome | associated_with | pathway | 0.60 |
| Pi3K/Akt | inhibits | pathway | 0.60 |
| Mapk | inhibits | pathway | 0.60 |
| Invasion | inhibits | pathway | 0.60 |
| Angiogenesis | inhibits | pathway | 0.60 |
| Adaptive Immunity | implicated_in | pathway | 0.60 |
| Complement | activates | pathway | 0.60 |
| Autophagy | therapeutic_target | pathway | 0.60 |
| Innate Immunity | activates | pathway | 0.60 |
| Jak-Stat | activates | pathway | 0.60 |
| Cell Cycle | associated_with | pathway | 0.60 |
| Oxidative Stress | causes | pathway | 0.60 |
| Gut Microbiome | causes | pathway | 0.60 |
| Mitophagy | associated_with | pathway | 0.60 |
| Jak-Stat | inhibits | pathway | 0.60 |
| Interferon Signaling | inhibits | pathway | 0.60 |
| Autophagy | interacts_with | pathway | 0.60 |
| Apoptosis | interacts_with | pathway | 0.60 |
| Cell Division | regulates | pathway | 0.60 |
| Cell Cycle | regulates | pathway | 0.60 |
| Immune Response | treats | pathway | 0.60 |
| Blood-Brain Barrier | therapeutic_target | pathway | 0.60 |
| Microrna | therapeutic_target | pathway | 0.60 |
| Inflammasome | activates | pathway | 0.60 |
| Ferroptosis | therapeutic_target | pathway | 0.60 |
| Oxidative Stress | associated_with | pathway | 0.60 |
| Lipid Metabolism | associated_with | pathway | 0.60 |
| Stem Cell | treats | pathway | 0.60 |
| Mtor | therapeutic_target | pathway | 0.60 |
| Pi3K/Akt | therapeutic_target | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Infection | activates | disease | 1.00 |
| VIRAL INFECTIONS | associated_with | gene | 1.00 |
| Infection | associated_with | disease | 1.00 |
| Infection | therapeutic_target | disease | 1.00 |
| VIRAL INFECTIONS | activates | gene | 0.95 |
| INFLAMMATION | activates | gene | 0.95 |
| VIRAL INFECTIONS | therapeutic_target | gene | 0.95 |
| CANCER | therapeutic_target | gene | 0.95 |
| INFLAMMATION | treats | gene | 0.85 |
| Als | activates | disease | 0.85 |
| INFLAMMATION | causes | gene | 0.85 |
| Als | causes | disease | 0.85 |
| VIRAL INFECTIONS | causes | gene | 0.85 |
| Cancer | therapeutic_target | disease | 0.85 |
| ISR Potentiators | treats | compound | 0.85 |
| Isr Potentiators | treats | compound | 0.85 |
| HNRNPA2B1 | involved_in | protein | 0.85 |
| HNRNPA1 | inhibits | protein | 0.80 |
| GENES | inhibits | gene | 0.75 |
| Als | therapeutic_target | disease | 0.75 |
| ALZHEIMER | associated_with | gene | 0.75 |
| INFLAMMATION | associated_with | gene | 0.75 |
| CANCER | associated_with | gene | 0.75 |
| Infection | treats | disease | 0.75 |
| PARKINSON'S DISEASE | implicated_in | gene | 0.75 |
| PARKINSON | implicated_in | gene | 0.75 |
| ALZHEIMER | activates | gene | 0.75 |
| ALZHEIMER DISEASE | activates | gene | 0.75 |
| NEURODEGENERATION | associated_with | gene | 0.75 |
| APOPTOSIS | activates | gene | 0.75 |
| PARKINSON | associated_with | gene | 0.75 |
| Infection | causes | disease | 0.75 |
| IFN | regulates | gene | 0.75 |
| VIRAL INFECTIONS | implicated_in | gene | 0.75 |
| Infection | implicated_in | disease | 0.75 |
| DNA | activates | gene | 0.75 |
| INFLAMMATION | interacts_with | gene | 0.75 |
| MITOCHONDRIA | activates | gene | 0.75 |
| Infection | contributes_to | disease | 0.75 |
| CYTOKINES | causes | gene | 0.75 |
| CANCER | activates | gene | 0.65 |
| INFLAMMATION | inhibits | gene | 0.65 |
| Tumor | inhibits | disease | 0.65 |
| CYTOKINES | associated_with | gene | 0.65 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.65 |
| AUTOPHAGY | associated_with | gene | 0.65 |
| AGING | associated_with | gene | 0.65 |
| Cancer | associated_with | disease | 0.65 |
| ERK1 | inhibits | gene | 0.65 |
| PTEN | inhibits | gene | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neuroinflammation | 2026-04-14 | 2 hypotheses Top: 0.499
neuroinflammation | 2026-04-13 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||